Michigan Pioneer Fellows Symposium
During the Annual Michigan Pioneer Fellows Symposium, we celebrate the invaluable research contributions of postdoctoral fellows and highlight the innovative work being done by Pioneer Fellows through engaging talks and a poster session. Whether you’re a fellow researcher, mentor, trainee or science enthusiast, this event offers a unique window into the future of scientific discovery at the University of Michigan.
Date: April 23, 2026
Time: 1:00 – 6:00 p.m.
Location: BSRB Kahn Auditorium
Schedule
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1:00 pm
Welcome and introductions
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1:05 pm
Talks by Pioneer Fellows
10-minute talks by Senior Pioneer Fellows from the 2023 Cohort: ● Guolei Zhao, Ph.D. ● Kristy Weaver, Ph.D. ● Jingcheng Wang, Ph.D. ● Morgan Pimm, Ph.D. ● Siva Kumar Natarajan, Ph.D. ● Jacob Moran, Ph.D. ● John Han, Ph.D. ● Fabio Gómez Cano, Ph.D. ● Brian Curtis, Ph.D. ● Christophe-Sebastien Arnold, Ph.D.
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3:30 pm
Keynote address: “New Approach Methodologies (NAMs) to Accelerate Clinical Trials in a Dish (CTiD)”
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4:30 pm
Poster session
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5:30 pm
Concluding remarks and reception
Keynote Address:
New Approach Methodologies (NAMs) to Accelerate Clinical Trials in a Dish (CTiD)
Joseph C. Wu, M.D., Ph.D.
Professor & Director, Stanford Cardiovascular Institute, Stanford University
Read the abstract
New Approach Methodologies (NAMs) to Accelerate Clinical Trials in a Dish (CTiD)
Drug discovery and development continue to face significant challenges, with over 90% of candidate drugs failing in clinical trials. These efficacy failures are primarily due to inherent species-specific differences, fundamental biological variances between model organisms and humans, and the limitations of existing models to accurately reflect the complexity of human disease and treatment responses. In this discussion, I will explore how the NIH and FDA are advocating for new alternative methodologies (NAMs) to reduce or replace animal testing. I will highlight recent advancements in technologies such as stem cells, organoids, and microphysiological systems (MPS), along with the roles of clinical genomics and AI/ML. Additionally, I will examine how these platforms can collaboratively enhance our understanding of rare orphan diseases, facilitate drug discovery, support precision medicine, and enable clinical trials in a dish (CTiD).
About the Speaker
Joseph C. Wu, MD, PhD is Director of Stanford Cardiovascular Institute and Simon H. Stertzer, MD, Professor of Medicine and Radiology at Stanford University. Dr. Wu received his MD from Yale University and PhD (Molecular & Medical Pharmacology) at University of California, Los Angeles. He is board certified in cardiovascular medicine. His lab works on genomics, stem cells/organoids, AI/ML, and drug discovery. The main goals are to (i) understand basic disease mechanisms, (ii) implement precision medicine for patients, and (iii) accelerate drug discovery via “new alternative methodologies” (NAMs) and “clinical trial in a dish” (CTiD) concept. Dr. Wu has published >700 manuscripts with H-index of 147 on Google scholar. He is listed as top 0.1% of highly cited researchers by Web of Science for past 7 years (2018-2024). Dr. Wu has received several awards, including the NIH Director’s New Innovator Award, NIH Roadmap Transformative Award, Presidential Early Career Award for Scientists and Engineers (PECASE) given out by President Obama at the White House, American Heart Association (AHA) Distinguished Scientist Award, AHA Merit Award, and Burroughs Wellcome Foundation Innovation in Regulatory Science Award. Dr. Wu serves on the FDA Cellular, Tissue, and Gene Therapies Advisory Committee. He is on the Board of the Keystone Symposia and American Heart Association. He is a past President of the American Heart Association (2023-2024). Dr. Wu is an elected member or fellow of the American Society for Clinical Investigation (ASCI), Association of University Cardiologists (AUC), American Institute for Medical and Biological Engineering (AIMBE), American Association of Physicians (AAP), Academia Sinica (Taiwan), American Association for the Advancement of Science (AAAS), Asian American Academy of Science and Engineering (AAASE), National Academy of Inventors (NAI), and National Academy of Medicine (NAM).
Past Symposia
Learn more about past themes and speakers, download posters from past years’ events.
2024 Symposium
Catherine Drennan, Ph.D., Professor of Chemistry and Biology, Massachusetts Institute of Technology; Investigator, Howard Hughes Medical Institute
2023 Symposium
Keynote Speaker: Sean Morrison, Ph.D., Founding Director, Children’s Medical Research Institute (CRI), University of Texas Southwestern Medical Center; Investigator, Howard Hughes Medical Institute Investigator
2022 Symposium
Keynote Speaker: Craig B. Thompson, M.D., Benno C. Schmidt Chair of Cancer Research, Memorial Sloan Kettering Cancer Center